GulfDoctor.net - A site for dermatologists & bioinformaticians by Bell Raj Eapen

STATEMENT OF RESEARCH INTERESTS
( Publications | Ongoing Projects )
Last Updated on 27-Aug-2008

As a dermatologist and bioinformatician my research mainly involves application of bioinformatics techniques and tools in dermatological conditions. My research interests are varied as I am interested in a wide range of theoretical and practical issues in dermatology. I have conducted most of my research as an independent researcher with no academic or industry affiliation. However I have worked for two years as an Asst. professor in a Harvard Medical International associated research institute in India. My CV is available online at http://www.gulfdoctor.net/resume.htm .

[Numbers in square bracket refers to the concerned publication in the list here]

Clinical Dermatology. [12, 13, 14, 15]
Clinical practice in two countries (India & United Arab Emirates) has given me good exposure to all skin types. During my post graduation, I have done research on patch test in footwear dermatitis and treatment options for SLE.
Artificial intelligence and its clinical applications [4, 9, 23]
I have always been fascinated by artificial intelligence algorithms like Bayesian belief networks and neural networks for which I have found applications in dermatological conditions. I have also developed a domain specific ontology called ONTODerm.
Genomics and Systems Biology [1, 2, 3, 5, 8, 22, 25]
I have extensively studied the genomic and systems biology aspects of several dermatological conditions and I have published several interesting findings.
Microarray analysis[3]
Immunology [27]
Mathematical modeling and computer programming.[26]
These areas are also of great interest to me, although I have done only limited research in it so far.
Structural bioinformatics and drug interactions [7, 24]
Ongoing work with Dr. Dedee Murrell (NSW, Australia) structural consequences of keratin mutations in Epidermolysis Bullosa Simplex.

Ongoing Research Projects.
( Publications )
Join Me!

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Serial No:	Title	Investigators	Start Date	Status	Wiki	SourceForge project page	Home Page	GulfDoctor ref no:	Biocore ref no:
01	ONTODerm - A domain ontology for dermatology.	Bell Eapen	10-June-2006	[Published] Eapen BR. Dermatology Online Journal 14 (6): 16 [Full Text] [Seeking dermatologists to join the project]	Click Here	Click here	Click Here
02	Malignancy in Dermatomyositis - A Bayesian Belief Network Approach.	Bell Eapen	10-October-2006	Published Eapen BR. Indian J Dermatol Venereol Leprol 2007;73:445-5 [Full Text]			Click Here
03	SLISED - Semantic LIterature SEarch for Dermatology.	Bell Eapen	25-July-2006	Planning	Click Here		Click Here
04	Photosensitivity in Smith-Lemli-Opitz syndrome: A flux balance analysis of altered metabolism.	Bell Eapen	29-October-2006	[Published] Eapen BR. Bioinformation 2 (2):78-82 (2007) [Full Text]			Click Here
05	MobBioTools - Bioinformatics Tools for Hand Held Devices	Bell Eapen	01-October-2007	Planning [Seeking Bioinformaticians with expertise in Java]	Wiki	Click Here [Bioinformatics.org]	Click Here
06	IISA - Intelligent Interface for Sequence Analysis	Bell Eapen	10-July-2006	Accepted for Frontiers in the Convergence of Bioscience and Information Technologies 2007 FBIT 2007 (Biologically Inspired Computation )	Click Here	Click here	Click Here IISA Web Interface	13	313
07	Novel Pathway level analysis of microarray expression data in psoriasis vulgaris	Safia, Bell Eapen	05-July-2006	Accepted for International Investigative Dermatology conference. (Kyoto, Japan) Eapen BR. Journal of Investigative Dermatology (Suppl). 2008; 128: S132 [Abstract - #787 [pdf]]				12	300
08	Genomic and biochemical modeling of melanin synthesis pathway using CADLIVE	Bell Eapen, Hussain Dohadwala	-	Abandoned					316
09	Melanocortin receptors and its regulators.	Bell Eapen	21-oct-2005	Protocol Completed				3	267
10	Effect of elastin mutations on its propensity for coacervation and its pathological significance.	Bell Eapen	06-nov-2005	Protocol Completed				6	269
11	Study of basement membrane zone proteins of unknown function.	Bell Eapen	Not Yet Started.
12	Finite element analysis of dental prosthesis.	Murali.S	Not Yet Started.					7
13	DermaMan - Dermatology Software for Hand Held Devices.	Bell Eapen	15-Sept-2007	Eapen BR. Indian J Dermatol Venereol Leprol. 2008 Jul-Aug;74(4):424-6. [Full Text ]			Home Page
14	Clinical Image analysis using MATLAB	Bell Eapen	17-Jan-2008	Prototype Completed			Home Page
15	ErBB2 receptors and Leprosy	Bell Eapen	08-Jan-2008	Eapen BR. Lepr Rev. 2008 Sep;79(3):335-7. [Full Text ]			Home Page
16	An agent based model of the functional dynamics of a cosmetic dermatology clinic using StarLogo-T.	Bell Eapen
17	Agent Based Modeling of Laser hair removal.	Bell Eapen	02-July-2008	Prototype Completed
18	Delayed-Type hypersensitivity to latex: Computational prediction of MHC class II epitopes on latex allergens	Bell Eapen	01-May-2008	Rejected			Home Page
19	Molecular Biology of Botulinum Toxin	Bell Eapen		[Published] Journal of cosmetic dermatology (2008). 7 ; 221-225 [Pubmed]
20	Pharmacophore Analysis of cutaneous drug reactions	Bell Eapen	02-July-2008
21	Evaluating the 'Aggressive Option' in dermatological therapeutics using Decisionoptions® methodology	Bell Eapen Gill Eapen	01-Aug-2008
22	Glycomics of Hyaluronic Acid based dermal fillers.	Bell Eapen	02-July-2008
23	Genomics of Hair Disorders.	Bell Eapen	11-Dec-2008	Planning
24	Online artificial intelligence tool for assistance in dermatological diagnosis.	Bell Eapen		Protocol Completed			Prototype	4	268

COMPLETED AND PUBLISHED WORK

[Pubmed Citations | Google Scholar Citations]